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Although single binary markers of senescence commitment have long been used in preclinical research, their utility as clinical parameters have so far been limited due to the wide-ranging heterogeneity of senescence in vivo , which often renders estimates of senescent cell quantification imprecise

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All procedures were in accordance with NIH guidelines and approved by the Rowan University Institutional Animal Care and use Committee

older athletic participants who had at least 3 h of exercise per week lasting one year, exhibited similar NAD + levels as healthy young participants

In the CNS, both neurons and glial cells express cGAS and STING, and their activation by mtDNA has been directly implicated in neuroinflammation and NDDs [12, 93]

Note that some peptides are restricted in competitive sports